Deterioration of sleep quality in the age of 40-60 years of age may be marker of Alzheimer’s disease

Ухудшение качества сна в возрасте 40-60 лет может быть маркером болезни Альцгеймера

Deteriorating sleep between the ages of 40 and 60 years may be due to the accumulation of beta-amyloid plaques in the brain, which, in most cases, marks Alzheimer’s disease in humans.

The study by researchers from the University of California at Berkeley showed that there is a relationship between the quality of nocturnal sleep in humans and the risk of suffering from Alzheimer’s disease.

“The decline in sleep quality in the age of 40-60 years can be a consequence of the accumulation of beta-amyloid plaques in the brain, the formation of which often precedes Alzheimer’s disease. Improving the quality of sleep, starting from middle age, is the prevention of dangerous diseases”, – cites the opinion of scientists on Medicalxpress.

According to the researchers, beta-amyloid and Tau proteins associated with development of neurodegenerative processes, are prognostic markers. Today, you can find them only allows expensive test PAT. Experts believe that sleep quality is a reliable reflector of the Central nervous system, and adverse changes in sleep quality after age 40 can be an early sign of dementia.

In turn, the improvement in sleep quality due to timely diagnosis and treatment of sleep apnea, which is associated with snoring and stops breathing during sleep, and cognitive-behavioral therapy for insomnia (CBT-I) is able to resist the development of Alzheimer’s disease, said the authors of the project.

“We hope that there will be a portable device that will provide all the necessary information about sleep – it will allow to estimate the level of proteins that cause Alzheimer’s disease”, said senior study author Matthew Walker.