Researchers from king’s College London has identified six main forms of disease caused by coronavirus, which differ from each other on the symptoms and severity of the disease. Three of these forms are transferred relatively easily and very rarely require respiratory support. You can not say about the sixth form – it accounts for the largest number of deaths.
The researchers analyzed data on symptoms observed at the 1,600 patients in the US and the UK. Carefully comparing the clinical manifestations of coronavirus in the first days of the disease with how it proceeded in the future, scientists have identified certain patterns. They saw that certain sets of symptoms at the initial stage of the disease to a considerable extent dictate how hard would it be to leak the disease and whether the patient will need respiratory support (that is, if he gets in the end on a ventilator). So in terms of the development of the disease in the first days were identified six different forms of COVID-19, informs television channel Sky News.
The first three form scientists have conventionally described as light, since only 1.5% to 4.4% of patients with such manifestations needed further respiratory support. When the first and second forms COVID-19 experience symptoms typical of the flu: headache, loss of smell, muscle aches, cough, sore throat, hoarseness, chest pain, loss of appetite. The first shape is different from the second only by one – all these symptoms can occur at normal temperature (the first form) and on the background of temperature rise (second).
In the first form only 1,5% of the patients required further respiratory support. In the second it was necessary in 4.4% of cases.
For the third form (gastro-intestinal) characters: headache, loss of smell, loss of appetite, diarrhea, sore throat, chest pain, no cough. Symptoms may develop on the background of fever, and without it. The key difference from the first two forms – diarrhea. Respiratory support in the case of this form takes an average 3.3% of cases.
The following forms identified by scientists as heavy. The fourth form symptoms: headache, loss of smell, cough, fever, hoarseness, chest pain, fatigue. It constant feeling of fatigue is a key symptom is typical for this form of the disease. The need for respiratory support here increases dramatically compared to the first three forms already for 8.6% of the patients will need special assistance in supporting the work of the lungs.
Symptoms of the fifth form: headache, loss of smell, loss of appetite, cough, fever, hoarseness, sore throat, chest pain, fatigue, confusion, muscle pain. Here’s to constant fatigue adds confusion. If these signs are observed in the first days of the disease, the probability of complications on the lungs with the need the hardware support their work increases to 9.9%.
Finally, the sixth, the most severe form of the disease the characters of the following symptoms in the first days of the disease: headache, loss of smell, loss of appetite, cough, fever, hoarseness, sore throat, chest pain, fatigue, confusion, muscle pain, shortness of breath, diarrhea, abdominal pain.
The probability for a ventilator or a more gentle form of breathing support is doubled, even compared with other severe forms was 19.8%.
“Our results are of great importance when monitoring patients who are most vulnerable to COVID-19, and provide them with medical care, said study co-author Dr. Claire Stevens. – If during the first five days to determine exactly who falls into this category, you will have time to start providing them extra help at an early stage and to be proactive, monitor the level of oxygen and blood sugar and replenish the fluid loss. All these are simple measures that you can take at home, without bringing the matter to hospitalization and save lives”.
According to the researchers, patients in whom was considered more severe forms COVID-19, on average, were older and were more related to poor health, the presence of excess weight and chronic diseases, including diabetes and respiratory diseases.