Doctors at the National hospital of Sri Lanka found that the coronavirus SARS-CoV-2 can cause disorders in the endocrine system, which may aggravate the condition of patients with the relevant disorders. About the new hazardous characteristic of the pathogen reported in a press release on EurekAlert!.
The specialists studied the condition of people who have been infected with a virus akin to SARS-CoV-1 that caused the outbreak of SARS in 2003. Many patients after the disease has developed postoronnii syndrome characterized by fatigue. Partly this could be caused by a dysfunction of the adrenal glands, which does not produce sufficient levels of cortisol. In turn, the reason could be malfunction of the pituitary system that regulates the adrenal glands. During the year the patients fully recovered.
Pathogenic properties of a novel coronavirus due to the fact that the pathogen binds to the human cell receptor, ACE2, are active in many tissues, including the endocrine system. It infects cells, causing a disruption in the production of hormones.
According to the researchers, testing for a deficiency of cortisol and treatment of patients with steroids can be a vital strategy against COVID-19. Has been shown to decrease mortality in critically ill patients with COVID-19 treated with the steroid dexamethasone.