An international group of scientists from USA, Germany and the UK have discovered a complex of NAC, which prevents the formation of protein aggregates that are characteristic in diseases such as Alzheimer’s disease, Huntington’s chorea and spinocerebellar ataxia.
According to the publication Science Daily, the function of NAC or polypeptide-associated complex, is the restoration of the proper structure of proteins and elimination of compounds with a defective structure.
It is able to detect prone to aggregation of the protein types, including hazardous polyglutamine (PolyQ), blocking it it prevents the formation of plaque and damage to nerve tissue.
This was confirmed by experiments on mice. The researchers analyzed their nerve cells with reduced levels of NAC.
It turned out that the cells were actively formed forms of PolyQ, which resulted in neurodegenerative consequences.