The scientists explained why about one-third of depressed patients do not perceive antidepressants

Ученые объяснили, почему около трети пациентов с депрессией не воспринимают антидепрессанты

People who develop depression are usually prescribed antidepressants. However, the body is about one-third of these patients did not respond to prescription drugs, according to American scientists have tried to deal with this problem, and found out the reason cells.

About a third of people who develop a severe form of depression complain that they feel positive effects after taking prescribed antidepressants. With this problem tried to figure out the experts of the Mayo clinic (Minnesota) and the Institute of biological research Salk (CA). As it turned out, the reason for the immunity of patients to antidepressants had to look in the cells. In the course of the study, the researchers compared the nerve cells that affects the brain to produce serotonin and its uses. At the biochemical level serotonin patients responsive and unresponsive to medications, differences were identified.

But in the cells was detected structural differences manifesting in the form of neurites and their growth. Note that the processes of nerve cell signals and transmitted to the brain and back. Scientists found that in cells from patients not responding to antidepressants, neurite outgrowth was much more than people normally perceive these drugs. That is why the medications and ineffective. According to the authors, their discovery should help doctors choose antidepressants more precisely, with the features of nerve cells of patients. Earlier, the doctors said what drinks should not take my pills.